Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932351 | Developmental Biology | 2012 | 8 Pages |
Abstract
⺠RA signaling participates in mammary gland initiation at appropriate time. ⺠RA prevents Lef1 expression possibly via effects on Wnt10b signalling. ⺠Raldh2 expression in leads to production of RA required for Tbx3 expression. ⺠RA signaling act Tbx3 expression via control of Fgf10 expression in somite. ⺠Tbx3 on Raldh2 protect the epithelium of developing mammary gland from RA.
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Authors
Kyoung-Won Cho, Hyuk-Jae Kwon, Jeong-Oh Shin, Jong-Min Lee, Sung-Won Cho, Cheryll Tickle, Han-Sung Jung,