Article ID Journal Published Year Pages File Type
10932351 Developmental Biology 2012 8 Pages PDF
Abstract
► RA signaling participates in mammary gland initiation at appropriate time. ► RA prevents Lef1 expression possibly via effects on Wnt10b signalling. ► Raldh2 expression in leads to production of RA required for Tbx3 expression. ► RA signaling act Tbx3 expression via control of Fgf10 expression in somite. ► Tbx3 on Raldh2 protect the epithelium of developing mammary gland from RA.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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