Article ID Journal Published Year Pages File Type
10932361 Developmental Biology 2012 14 Pages PDF
Abstract
► Smooth muscle α-actin (Acta2) −/− dams exhibit a nursing phenotype. ► Pups nursed by Acta2−/− dams are unable to thrive postpartum. ► Acta2−/− mammary glands exhibit precocious involution. ► Developmental reduction of myoepithelial cells in Acta2−/− mammary glands. ► Acta2 mediates myoepithelial contraction in an isoform specific manner.
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