Article ID Journal Published Year Pages File Type
10932362 Developmental Biology 2012 12 Pages PDF
Abstract
► Dan is expressed in the left side of the node. ► DAN inhibits BMP signaling but not NODAL signaling. ► Dan is indispensable for Nodal in the LPM and for Lefty-1 in the notochord. ► Nodal up-regulation by DAN requires NODAL signaling. ► DAN might act synergistically with NODAL to induce Nodal and Lefty-1.
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