Article ID Journal Published Year Pages File Type
10932371 Developmental Biology 2012 11 Pages PDF
Abstract
► Cytokines and sensory systems: MIF has a critical role affecting inner ear innervation. ► Otocyst cytokines influence inner ear neuron directional outgrowth and survival. ► Embryonic and adult inner ear neurons express neurotrophic cytokine MIF receptors (R). ► Blocking MIF or MIF R with morpholinos profoundly affects inner ear development. ► MIF effects are mediated at least partially through p53 pathways.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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