Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932372 | Developmental Biology | 2012 | 11 Pages |
Abstract
⺠The scaffold protein β Pix requires Git1-binding ability to stabilize blood vessels. ⺠Knockdown of β Pix , Git1 or Integrin αvβ8 results in hemorrhage. ⺠β Pix and Integrin αvβ8 promote cerebral angiogenesis. ⺠β Pix and Integrin αvβ8 promote proliferation of endothelial and mesenchymal cells. ⺠Loss of β Pix or Integrin αvβ8 leads to lower vascular mural cell marker expression.
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Authors
Jing Liu, Lei Zeng, Regan M. Kennedy, Nicole M. Gruenig, Sarah J. Childs,