| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932391 | Developmental Biology | 2012 | 11 Pages |
Abstract
⺠Canonical Smad1/Smad5 signaling functions redundantly in BMP-regulated AER functions. ⺠Syndactyly of Smad1/5 mutant: reduction in PCD and increase in cell proliferation. ⺠The epithelial-mesenchymal interaction regulates the interdigital regression. ⺠Prolonged Fgf8 expression in Smad1/5 mutants as survival signal to interdigital cells ⺠Ventral ectoderm thickened after Smad1/5 inactivation and located ectopically dorsal.
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Authors
Yuk Lau Wong, Richard R. Behringer, Kin Ming Kwan,