| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932416 | Developmental Biology | 2012 | 9 Pages |
Abstract
⺠The head skeleton is a “product” of the early neural primordium. ⺠Hox gene expression by the facial neural crest prevents head development. ⺠The removal of the Hox-negative neural crest depletes Fgf8 in brain organizers. ⺠The production of Fgf8 in the ANR, isthmus and BA1 ectoderm by the cephalic NC. ⺠Brain and face form a “developmental unit” under the control of the neural crest.
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Authors
Nicole M. Le Douarin, Gérard Couly, Sophie E. Creuzet,