Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932433 | Developmental Biology | 2011 | 15 Pages |
Abstract
⺠3 homologues to EGF receptors are reported in the planarian Schmidtea mediterranea. ⺠Smed-egfr-1 is required for eye-pigment cells and pharynx regeneration. ⺠Smed-egfr-1(RNAi) results in hyperproliferation and development of dorsal outgrowths. ⺠Smed-egfr-3 is expressed in stem cells and differentiated cell types. ⺠Smed-egfr-3(RNAi) inhibits blastema formation and cell differentiation.
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Authors
Susanna Fraguas, Sara Barberán, Francesc Cebrià ,