| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932436 | Developmental Biology | 2011 | 12 Pages |
Abstract
⺠Sox9 is a key gene required for male development. ⺠A viable mouse model of Sox9 loss-of-function exhibits male-to-female sex reversal. ⺠XY follicles develop but their number is reduced. ⺠XY oocytes fail to pass two-cell stage with mitotic cells which do not separate. ⺠Although Sox9 is expressed in ovaries, Sox9 is dispensable for fertility in females.
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Authors
Rowena Lavery, Aurélie Lardenois, Fariba Ranc-Jianmotamedi, Eva Pauper, Elodie P. Gregoire, Caroline Vigier, Chimene Moreilhon, Michael Primig, Marie-Christine Chaboissier,