Article ID Journal Published Year Pages File Type
10932450 Developmental Biology 2011 10 Pages PDF
Abstract
► Activated Notch inhibits the differentiation of corticotropes and melanotropes. ► Activated Notch induces the expression of progenitor markers in POMC cells. ► Melanotropes and corticotropes fail to regenerate. ► Improper Notch signaling in corticotropes leads to dysfunction of the HPA axis.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis
Authors
, , ,