Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932462 | Developmental Biology | 2011 | 12 Pages |
Abstract
⺠KLF5 is required for stratification and terminal differentiation of urothelial cells. ⺠Defects in urothelial maturation induces hydronephrosis. ⺠KLF5 is not required for maturation of the bladder neck and urethral epithelium. ⺠Grhl3 and Pparγ are candidate targets of KLF5 during urothelial maturation. ⺠KLF5 regulates paracrine interactions with bladder mesenchyme.
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Authors
Sheila M. Bell, Liqian Zhang, Angela Mendell, Yan Xu, Hans Michael Haitchi, James L. Lessard, Jeffrey A. Whitsett,