Article ID Journal Published Year Pages File Type
10932462 Developmental Biology 2011 12 Pages PDF
Abstract
► KLF5 is required for stratification and terminal differentiation of urothelial cells. ► Defects in urothelial maturation induces hydronephrosis. ► KLF5 is not required for maturation of the bladder neck and urethral epithelium. ► Grhl3 and Pparγ are candidate targets of KLF5 during urothelial maturation. ► KLF5 regulates paracrine interactions with bladder mesenchyme.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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