| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932469 | Developmental Biology | 2011 | 9 Pages |
Abstract
⺠Misexpression of zebrafish Atoh1a promotes sensory development in the otic vesicle. ⺠Responsiveness to Atoh1a is spatially restricted at all stages and declines with age. ⺠Misexpression of Sox2 or Fgf3/8 greatly expands the zone of responsiveness to Atoh1a. ⺠Sox2 enhances prosensory activity of Atoh1a even at relatively late stages. ⺠Atoh1a acts in a gene network with Fgf and Sox2 to promote sensory development.
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Authors
Elly M. Sweet, Shruti Vemaraju, Bruce B. Riley,