Article ID Journal Published Year Pages File Type
10932477 Developmental Biology 2011 13 Pages PDF
Abstract
►DSulf1 is a regulator of Hedgehog signalling during wing development. ►DSulf1 is expressed both in Hh producing and receiving cells. ►DSulf1 positively regulates Hh signalling in the source of the morphogen. ►DSulf1 negatively regulates Hh signalling in its target field. ►Our data evidence a novel Hh regulatory feedback loop, involving DSulf1.
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