Article ID Journal Published Year Pages File Type
10932481 Developmental Biology 2011 12 Pages PDF
Abstract
► The E3 ubiquitin ligase Fbw7 is required for cerebellar development. ► Fbw7 deletion increases N-terminally phosphorylated c-Jun and Notch1 protein levels. ► Concomitant c-Jun deletion partially rescues cerebellar defects in Fbw7-mutant mice.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
, , , , , ,