Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932490 | Developmental Biology | 2011 | 15 Pages |
Abstract
⺠Hh/Gli signals are critical for neural induction in Xenopus. ⺠Sufu regulates neural induction, anteroposterior patterning, and eye development. ⺠Sufu is sufficient and required to inhibit Wnt/β-catenin signaling in vivo. ⺠Gli1 suppresses Wnt and β-catenin stimulates Hh signaling in the embryo. ⺠Sufu is critical for the crosstalk between Hh and Wnt signals.
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Authors
Tan H. Min, Martin Kriebel, Shirui Hou, Edgar M. Pera,