Article ID Journal Published Year Pages File Type
10932490 Developmental Biology 2011 15 Pages PDF
Abstract
► Hh/Gli signals are critical for neural induction in Xenopus. ► Sufu regulates neural induction, anteroposterior patterning, and eye development. ► Sufu is sufficient and required to inhibit Wnt/β-catenin signaling in vivo. ► Gli1 suppresses Wnt and β-catenin stimulates Hh signaling in the embryo. ► Sufu is critical for the crosstalk between Hh and Wnt signals.
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