Article ID Journal Published Year Pages File Type
10932501 Developmental Biology 2011 12 Pages PDF
Abstract
► This study surveys epigenetic marks in the early C. elegans embryo. ► We found that H3K4me3 is almost undetectable in germline blastomeres. ► We also found that a limited number of somatic blastomeres are devoid of H3K4me3. ► H3K4me3 is deposited by the MLL complex and antagonised by PIE-1 > Embryonic H3K4me3 deposition is a dynamic and highly regulated process.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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