Article ID Journal Published Year Pages File Type
10932507 Developmental Biology 2011 11 Pages PDF
Abstract
► Porcn is required for canonical Wnt signaling in mouse embryonic stem cells. ► Porcn mutant mouse embryos fail to complete gastrulation. ► Porcn mutant embryoid bodies fail to generate endoderm and mesoderm in vitro.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos
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