Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932513 | Developmental Biology | 2011 | 10 Pages |
Abstract
⺠Flrt3 expression during limb development is restricted to the AER. ⺠Flrt3 expression coincides with that of fgf8 and pERK activity. ⺠Flrt3 is necessary but not sufficient for proper AER formation and maintenance. ⺠Flrt3 expression is not regulated by FGF activity. ⺠Ectopic Wnt3a is able to induce flrt3; BMPs specifically inhibit flrt3 in the AER.
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Authors
Ana Raquel Tomás, Ana Catarina Certal, JoaquÃn RodrÃguez-León,