Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932533 | Developmental Biology | 2012 | 10 Pages |
Abstract
⺠Orai1 is a calcium channel in the plasma membrane of oocytes. ⺠It mediates store-operated calcium entry upon depletion of the endoplasmic reticulum. ⺠The calcium influx through the Orai1 channel is essential for maintaining calcium oscillations during fertilization. ⺠After fertilization, oocytes lacking Orai1 form embryos with poor developmental potential.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Chunmin Wang, Kiho Lee, Erzsébet Gajdócsi, Ágnes Bali Papp, Zoltan Machaty,