Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932543 | Developmental Biology | 2012 | 18 Pages |
Abstract
⺠BMP signaling promotes extraembryonic endoderm stem (XEN) cell epithelialization. ⺠BMP4-treated XEN cells acquire an extraembryonic visceral endoderm identity. ⺠Effect of BMP4 is reversible and is antagonized by LIF signaling. ⺠Fluctuation of Afp::GFP expression reveals a dynamic equilibrium upon BMP4 stimulation. ⺠XEN cells promote primitive erythroid progenitor (EryP) expansion.
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Authors
Jérôme Artus, Panagiotis Douvaras, Anna Piliszek, Joan Isern, Margaret H. Baron, Anna-Katerina Hadjantonakis,