Article ID Journal Published Year Pages File Type
10932543 Developmental Biology 2012 18 Pages PDF
Abstract
► BMP signaling promotes extraembryonic endoderm stem (XEN) cell epithelialization. ► BMP4-treated XEN cells acquire an extraembryonic visceral endoderm identity. ► Effect of BMP4 is reversible and is antagonized by LIF signaling. ► Fluctuation of Afp::GFP expression reveals a dynamic equilibrium upon BMP4 stimulation. ► XEN cells promote primitive erythroid progenitor (EryP) expansion.
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