Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932544 | Developmental Biology | 2012 | 14 Pages |
Abstract
⺠DNA damage accumulates in irradiated p53 mutants, impairing regeneration. ⺠Cell death is not necessary for induction of regeneration. ⺠During regeneration cell division continues at a developmentally programmed pace. ⺠Irradiation induces p53-dependent larval timing and disc patterning checkpoints. ⺠Compensatory proliferation is not restricted to the larval stage of development.
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Authors
Brent S. Wells, Laura A. Johnston,