Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932550 | Developmental Biology | 2012 | 11 Pages |
Abstract
⺠Polarization specifies the Wnt signaling response of the C. elegans Q neuroblasts. ⺠Posterior polarization sensitizes for canonical Wnt/β-catenin pathway activation. ⺠Polarization is dependent on the TSP repeat protein MIG-21. ⺠MIG-21 acts cell autonomously in the Q neuroblasts during the polarization process. ⺠MIG-21 functions together with the netrin receptor UNC-40/DCC.
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Authors
Teije C. Middelkoop, Lisa Williams, Pei-Tzu Yang, Jeroen Luchtenberg, Marco C. Betist, Ni Ji, Alexander van Oudenaarden, Cynthia Kenyon, Hendrik C. Korswagen,