Article ID Journal Published Year Pages File Type
10932550 Developmental Biology 2012 11 Pages PDF
Abstract
► Polarization specifies the Wnt signaling response of the C. elegans Q neuroblasts. ► Posterior polarization sensitizes for canonical Wnt/β-catenin pathway activation. ► Polarization is dependent on the TSP repeat protein MIG-21. ► MIG-21 acts cell autonomously in the Q neuroblasts during the polarization process. ► MIG-21 functions together with the netrin receptor UNC-40/DCC.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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