Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932569 | Developmental Biology | 2011 | 11 Pages |
Abstract
⺠S1P1 is expressed by the blood vessels in developing endoderm. ⺠S1P1 ablation results in compromised growth of several foregut-derived organs. ⺠Reduced growth in the pancreas results from decreased proliferation of Pdx1+ cells. ⺠Blood vessel ablation does not mimic the S1P1â/â instead the opposite is observed. ⺠Hypervascularization is seen in the S1P1 mutants.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Fredrik Wolfhagen Sand, Andreas Hörnblad, Jenny K. Johansson, Christina Lorén, Josefina Edsbagge, Anders StÃ¥hlberg, Judith Magenheim, Ohad Ilovich, Eyal Mishani, Yuval Dor, Ulf Ahlgren, Henrik Semb,