| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932570 | Developmental Biology | 2011 | 10 Pages |
Abstract
⺠Cul4Aâ/â male mice are infertile due to severe deficiencies in spermatogenesis. ⺠Loss of CUL4A disrupts meiosis at the end of prophase I and increases cell death. ⺠Cul4Aâ/â pachytene spermatocytes exhibit persistent DSBs signifying deficient HR. ⺠CUL4A localizes to the sites of DSBs, suggesting a direct role in HR.
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Authors
Dragana Kopanja, Nilotpal Roy, Tanya Stoyanova, Rex A. Hess, Srilata Bagchi, Pradip Raychaudhuri,