Article ID Journal Published Year Pages File Type
10932576 Developmental Biology 2011 12 Pages PDF
Abstract
►Lrrn1 is expressed in midbrain cells but not in anterior hindbrain cells. ►Lrrn1 is down-regulated in anterior hindbrain by FGF8. ►Lrrn1 creates a differential affinity between midbrain and hindbrain compartments. ►This forms a sharp compartment boundary at the midbrain-hindbrain interface. ►Lrrn1 is required for formation of the mid-hindbrain boundary.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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