Article ID Journal Published Year Pages File Type
10932578 Developmental Biology 2011 15 Pages PDF
Abstract
►Goosecoid transcription is directly activated by Siamois and Twin. ►Siamois and Twin bind a conserved P3 site of the endogenous Goosecoid promoter. ►Siamois-Twin homodimers and heterodimers have equivalent function. ►Siamois and Twin are redundant and essential for Spemann organizer formation. ►The transcriptional response to maternal Wnt signals is mediated by Siamois and Twin.
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