| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932585 | Developmental Biology | 2011 | 4 Pages |
Abstract
⺠EGFR receptor signaling in insects is regulated, to a large extent, by processing of the ligands. ⺠Variations in intracellular localization of the proteases cleaving the ligands were identified. ⺠These variations impinge on the amount of secreted ligand, as well as on the polarity of secretion. ⺠The processing cassette was examined in different insect species. ⺠It traces the elaboration of this pathway, and diversification of its regulation.
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Authors
Shaul Yogev, Tal Rousso, Eyal D. Schejter, Ben-Zion Shilo,