| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932596 | Developmental Biology | 2011 | 16 Pages |
Abstract
⺠The function of boule genes is shown for the first time in a lophotrochozoan. ⺠There are three distinct macbol orthologues in the flatworm Macrostomum lignano. ⺠Macbol1 and macbol2 are testis-specific, macbol3 is essential for oogenesis. ⺠RNAi arrests male meiosis (macbol1) and impedes egg maturation (macbol3). ⺠Macbol1 is able to rescue meiotic divisions in boule-mutant Drosophila melanogaster.
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Authors
Georg Kuales, Katrien De Mulder, Jade Glashauser, Willi Salvenmoser, Shigeo Takashima, Volker Hartenstein, Eugene Berezikov, Walter Salzburger, Peter Ladurner,