| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932608 | Developmental Biology | 2011 | 13 Pages |
Abstract
⺠vgll2a is expressed in the pharyngeal endoderm and ectoderm surrounding the neural crest derived mesenchyme of the pharyngeal arches. ⺠FGF and retinoic acid (RA) signaling pathways regulate this domain of vgll2a expression. ⺠vgll2a is required within the pharyngeal epithelia for NCC survival and development of the cranial cartilages. ⺠These data reveal a novel non-cell autonomous role for Vgll2a in development of the NCC-derived vertebrate craniofacial skeleton.
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Authors
Christopher W. Johnson, Laura Hernandez-Lagunas, Weiguo Feng, Vida Senkus Melvin, Trevor Williams, Kristin Bruk Artinger,