Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932614 | Developmental Biology | 2011 | 13 Pages |
Abstract
⺠Snai1 is required for cell transformation and motility during cushion EMT. ⺠MMP15 promotes cell motility, but not transformation during cushion EMT. ⺠MMPs are required for Snai1-mediated cell migration during cushion EMT. ⺠MMP15 activity rescues cell migration defects in cushions following snai1 knockdown. ⺠Snai1 binds and regulates E-box rich regions within the mmp15 gene.
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Authors
Ge Tao, Agata K. Levay, Thomas Gridley, Joy Lincoln,