Article ID Journal Published Year Pages File Type
10932622 Developmental Biology 2011 18 Pages PDF
Abstract
► Genetic and embryologic origin of muscle fiber-type diversity remains unknown in mammals. ► We investigate the role of Six proteins in the genetic of muscle fiber-type diversity. ► We establish the gene network controlled by Six1/4 proteins in mouse E18 embryo. ► Six control crosstalk between slow and fast type determinant genes. ► Six are required for genesis of muscle fiber type diversity during embryogenesis.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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