Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932622 | Developmental Biology | 2011 | 18 Pages |
Abstract
⺠Genetic and embryologic origin of muscle fiber-type diversity remains unknown in mammals. ⺠We investigate the role of Six proteins in the genetic of muscle fiber-type diversity. ⺠We establish the gene network controlled by Six1/4 proteins in mouse E18 embryo. ⺠Six control crosstalk between slow and fast type determinant genes. ⺠Six are required for genesis of muscle fiber type diversity during embryogenesis.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Anne-Françoise Richard, Josiane Demignon, Iori Sakakibara, Julien Pujol, Maryline Favier, Laure Strochlic, Fabien Le Grand, Nicolas Sgarioto, Anthony Guernec, Alain Schmitt, Nicolas Cagnard, Ruijin Huang, Claire Legay, Isabelle Guillet-Deniau,