Article ID Journal Published Year Pages File Type
10932626 Developmental Biology 2011 7 Pages PDF
Abstract
► Dicer is essential for paraxial mesodermal cell survival. ► Dicer is essential for establishing rostral-caudal polarity of somites. ► Paraxial mesoderm segmentation occurs in the absence of Dicer. ► Dicer is essential for limb bud positioning. ► Dicer may act via miRNAs to control Hand2/Tbx3 expression and limb positioning.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning
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