Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932628 | Developmental Biology | 2011 | 10 Pages |
Abstract
⺠The Del7AI deletion causes an imprinted intrauterine growth restriction phenotype. ⺠Expression of the imprinted gene Ascl2 is reduced in Del7AI maternal heterozygotes. ⺠Phlda2 expression is upregulated in Ascl2 hypomorphic placentae. ⺠Del7AI alters the three layers of the mature placenta. ⺠The mutant placentae lack trophoblast glycogen cells.
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Authors
Rosemary Oh-McGinnis, Aaron B. Bogutz, Louis Lefebvre,