| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932629 | Developmental Biology | 2011 | 9 Pages |
Abstract
⺠We generate a large inversion allele, on the centromeric side of the HoxD cluster. ⺠The centromeric landscape is flipped away, while leaving the cluster intact. ⺠This inversion causes shortening of both primary and secondary body axes. ⺠Mis-regulations of Hoxd genes underlie the observed phenotypes ⺠We discuss the importance of genomic “landscape effects” on gene regulation.
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Authors
Patrick Tschopp, Denis Duboule,