Article ID Journal Published Year Pages File Type
10932638 Developmental Biology 2011 16 Pages PDF
Abstract
► MURF muscle ubiquitin ligases are developmentally regulated in mouse heart. ► MURF2 is the dominant cardiac MURF isogene expressed from mouse E8.5 onwards. ► MURF2 regulates microtubule dynamics in cardiac sarcomere assembly in vitro. ► MURF 2 and 3 show partial functional compensation in sarcomere assembly.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover
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