| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932651 | Developmental Biology | 2011 | 10 Pages |
Abstract
⺠Previous studies suggested that FGF signaling is important for lens formation. ⺠We conditionally deleted FGF receptors to test the role of FGFs in lens induction. ⺠Fgfr1/2 deletion greatly increased cell death at the onset of lens induction. ⺠Pax6 and other lens cell markers were not reduced in the lens placode. ⺠FGF signaling is important for lens cell survival, but not for lens induction.
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Authors
Claudia M. Garcia, Jie Huang, Bhavani P. Madakashira, Ying Liu, Ramya Rajagopal, Lisa Dattilo, Michael L. Robinson, David C. Beebe,