Article ID Journal Published Year Pages File Type
10932659 Developmental Biology 2011 8 Pages PDF
Abstract
► Ascl3+ cells are proliferating progenitors of acinar and duct cells. ► Knockout of Ascl3 does not alter the bipotency of the progenitor cells. ► Salivary glands develop in the absence of ablated Ascl3+ progenitor cells. ► Ascl3+ progenitor cells are not required for regeneration of the salivary glands.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration
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