| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932660 | Developmental Biology | 2011 | 12 Pages |
Abstract
⺠The parathyroid glands originate from the Gcm2-expressing caudal pharyngeal pouches. ⺠Fish, chick and mouse show highly reduced Shh signalling where Gcm2 is expressed. ⺠During early development, HH signalling reduction results in the loss of chick Gcm2. ⺠Later on, it induces ectopic Gcm2 in the second and first pharyngeal epithelium. ⺠A conserved regulatory mechanism of Gcm2 by HH signalling defines pouch derivatives.
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Authors
Armelle Grevellec, Anthony Graham, Abigail S. Tucker,