Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932663 | Developmental Biology | 2011 | 13 Pages |
Abstract
⺠Gata4 is required for testis differentiation and for the expression of Dmrt1 gene. ⺠Gonadal loss of Fog2 results in a partial block in the male pathway and sex reversal. ⺠Testis sexual differentiation is sensitive to the timing of GATA4 loss. ⺠Gata4 and Fog2 genes have non-overlapping essential functions in testis development.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
N.L. Manuylov, B. Zhou, Q. Ma, S.C. Fox, W.T. Pu, S.G. Tevosian,