Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932664 | Developmental Biology | 2011 | 17 Pages |
Abstract
⺠Six1 is expressed in lung distal epithelium and mesenchyme. ⺠Six1â/â lungs are hypoplastic with reduced branching. âºSix1 controls both epithelial and mesenchymal cell proliferation. ⺠Six1 induces epithelial progenitor cell proliferation but inhibits differentiation. ⺠Six1 coordinates Shh-Fgf10 signaling during lung development.
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Authors
Ahmed H.K. El-Hashash, Denise Al Alam, Gianluca Turcatel, Orquidea Rogers, Xue Li, Saverio Bellusci, David Warburton,