Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932666 | Developmental Biology | 2011 | 9 Pages |
Abstract
⺠We reveal Hox gene expression in the second heart field (SHF). ⺠Expression of Hox genes in the SHF defines new cardiac progenitor sub-domains. ⺠Contribution of cardiac Hox-positive cells demonstrates pre-patterning of the SHF. ⺠Expression of Hox genes in the SHF depends on Retinoic Acid (RA) signaling. ⺠Cardiac contributions of Hox-positive SHF cells are RA sensitive.
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Authors
Nicolas Bertrand, Marine Roux, Lucile Ryckebüsch, Karen Niederreither, Pascal Dollé, Anne Moon, Mario Capecchi, Stéphane Zaffran,