Article ID Journal Published Year Pages File Type
10932672 Developmental Biology 2011 13 Pages PDF
Abstract
► Nav2 is required for normal cerebellar development. ► Nav2/unc-53H2 homozygous mutants (Nav2−/−) are ataxic. ► The size of the cerebellum is reduced and foliation is disrupted in Nav2−/− mutants. ► Disappearance of the EGL in homozygous Nav2−/− mutants is delayed. ► Axon extension and migration of granule cells is defective in Nav2−/− mutants.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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