Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10932688 | Developmental Biology | 2011 | 11 Pages |
Abstract
⺠The secreted Wnt signal antagonist Dkk1 is expressed in the cells of developing ureteric tree and the nephrons. ⺠Dkk1 function is critical for development of the papilla of the kidney as judged by Pax8Cre mediated knock out of Dkk1 function. ⺠Dkk1 may coordinate papilla development by fine tuning the action of Wnt-7b signalling.
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Authors
Ilkka Pietilä, Kristina Ellwanger, Antti Railo, Tiina Jokela, Ivan del Barco Barrantes, Jingdong Shan, Christof Niehrs, Seppo J. Vainio,