| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932692 | Developmental Biology | 2011 | 11 Pages |
Abstract
⺠The otic placode is enlarged in Sprouty1, Sprouty2 compound mutants. ⺠This enlargement is due to the recruitment of cells into the otic domain. ⺠Sprouty1, 2 transcripts are present in tissues responsive to FGF signals. ⺠Wnt8a expression in the hindbrain is expanded in Sprouty1, 2 compound mutants. ⺠Sprouty1, 2 antagonize FGF10 induction of the otic placode and Wnt8a expression.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Amanda A. Mahoney Rogers, Jian Zhang, Katherine Shim,