Article ID Journal Published Year Pages File Type
10932741 Developmental Biology 2011 13 Pages PDF
Abstract
► The loss of FGF signaling in the midbrain leads to increased neurogenesis. ► FGFs maintain Hes1 expression in midbrain ventricular zone. ► FGF-deficient progenitors begin to form symmetrical neurogenic divisions. ► FGFR1/2- signaling affects neuronal progenitors cell-autonomously. ► FGF8-protein gradient localizes in the basal lamina.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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