| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10932786 | Developmental Biology | 2011 | 11 Pages |
Abstract
⺠BmprIa and BmprIb show partially overlapped expression patterns in developing palate and tooth. ⺠BmprIa deletion by Wnt1-Cre leads anterior clefting of the palate and arrested tooth development. ⺠Transgenic BmprIb partially rescues tooth defects but not palate defect in mice lacking BmprIa. ⺠We conclude that BmprIa is essential in mesenchymal compartment for palate and tooth development. ⺠BmprIb functions redundantly with BmprIa in a tissue-specific manner in craniofacial development.
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Authors
Lu Li, Minkui Lin, Ying Wang, Peter Cserjesi, Zhi Chen, YiPing Chen,