| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10939455 | Fungal Genetics and Biology | 2012 | 13 Pages |
Abstract
⺠A mode of action of amiodarone for filamentous fungus Aspergillus niger is proposed. ⺠The effect of amiodarone on intracellular calcium kinetics and pH was analyzed. ⺠Calcium ATPase pmrAΠand pmcAΠmutants are hypersensitive to amiodarone. ⺠Hypersensitivity correlates with cytosolic calcium resting level. ⺠Irregular [Ca2+]c and intracellular acidification decrease cell viability.
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Authors
Tanja Bagar, Mojca BenÄina,