Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10939518 | Fungal Genetics and Biology | 2012 | 7 Pages |
Abstract
⺠A Yarrowia lipolytica mutant deleted in 12 P450ALK genes (Îalk1-12) was constructed. ⺠Îalk1-12 did not grow on n-alkanes, but grew on their metabolites. ⺠Îalk1-12 failed to convert n-dodecane to n-dodecanoic acid. ⺠P450ALKs are indispensable for n-alkane oxidation. ⺠Transcriptional activation of ALK1 by n-alkane was independent of P450ALKs.
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Authors
Hiroshi Takai, Ryo Iwama, Satoshi Kobayashi, Hiroyuki Horiuchi, Ryouichi Fukuda, Akinori Ohta,