| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10939531 | Fungal Genetics and Biology | 2011 | 9 Pages |
Abstract
⺠Pc22g24830/PcoahA encodes oxaloacetase activity in Penicillium chrysogenum. ⺠PcoahA is negatively regulated by phenylacetate. ⺠Expression of PcoahA in yeast demonstrates its sufficiency for oxaloacetase activity. ⺠Deletion of PcoahA leads to elimination of oxalate production in P. chrysogenum. ⺠PcoahA deletion affects positively synthesis of cephalosporin intermediate ad-6-APA.
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Authors
A.K. Gombert, T. Veiga, M. Puig-Martinez, F. Lamboo, J.G. Nijland, A.J.M. Driessen, J.T. Pronk, J.M. Daran,