Article ID Journal Published Year Pages File Type
10940658 Immunobiology 2016 7 Pages PDF
Abstract
In this review we will focus on the links between complement and autoimmune diseases and will highlight how animal models have provided insights into the manner by which C1q and C3 act to modulate both adaptive and innate immune responses. In particular we will highlight how C1q may not only act as initiator of the classical complement pathway, but can also mediate multiple immune responses in a complement activation independent manner.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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